Radiolab has a humorous hour of interviews about how humans can exceed their own limits by studying them and then breaking through (e.g. hacking the body, mind and knowledge)

On this hour of Radiolab: a journey to the edge of human limits.

How much can you jam into a human brain? How far can you push yourself past feelings of exhaustion? We test physical endurance with a bike race that makes the Tour de France look like child’s play, and mental capacity with a mind-stretching memory competition. And we ask if robots–for better or worse–may be forging beyond the limits of human understanding.